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KMID : 0043320090320020195
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Archives of Pharmacal Research
2009 Volume.32 No. 2 p.195 ~ p.200
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Antioxidant Activities of New Flavonoids from Cudrania tricuspidata Root Bark
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Whang Wan-Kyunn
Ham In-hye
Lee Sung-Jae
Kim Sung-Gun
Lee Young-Jae
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Abstract
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Two new flavonoids, hydroxybenzyl flavonoid glycosides (6-p-hydroxybenzyl kaempferol-7-O-β-Dglucopyranoside named cudranian 1 and 6-p-hydroxybenzyl quercetin-7-O-β-D-glucopyranoside named cudranian 2), and 3 known flavonoids (kaempferol-7-O-β-D-glucopyranoside, quercetin-7-O-β-D-glucopyranoside and aromadendrin) were isolated from root bark of Cudrania tricuspidata and their structures were elucidated by spectroscopic methods. These compounds showed remarkable radical scavenging effects against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and anti-lipid peroxidation efficacy on human low-density lipoprotein by TBARS assay.
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KEYWORD
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Cudrania tricuspidata (Moraceae), 6-p-Hydroxybenzyl kaempferol-7-O-β-D-glucopyranoside (cudranian 1), 6-p-Hydroxybenzyl quercetin-7-O-β-D-glucopyranoside (cudranian 2), Anti-oxidative activity
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